PRODUCT CATEGORY

Thermo Scientific ProPac SAX-10 LC Columns

Description

 

Use Thermo Scientific™ ProPac™ SAX-10 LC Columns for exceptionally high resolution and efficiency when separating protein variants. Based on a nonporous 10µm core particle that provides pressure stability, ProPac columns can resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer prevents unwanted secondary interactions. The grafted anion-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

 

Maximizing Resolution
  • ProPac SAX-10 LC column is a strong anion-exchanger with a quaternary amine functional group.
  • Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semiprep work.

Superior Performance for Protein Analysis
  • Ideal for characterization and quality control assessment of closely-related protein variants
  • Unequaled high-resolution separations
  • High-efficiency peaks with excellent recovery
  • Higher capacity than other columns based on nonporous particles
  • Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing

Specifications

Analytical Column
4mm
LC
3000psi
Polymer, Spherical Nonporous
2 to 12
60°C
Protein/Anion Exchange
Ion Exchange
1mL/min.
250mm
pH 2-12, 80% Compatible with Acetonitrile, Acetone, Methanol, Compatible with Nonionic and Zwitterionic Detergents, Incompatible with Anionic Detergents
10μm
Nonporous
N/A
Quaternary Ammonium